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What is Crocarmellose Sodium?

 

Croscarmellose Sodium or Sodium CMC is a fibrous powder used as a non-active ingredient in prescription medications. It has been approved by the Food and Drug Administration as a pharmaceutical additive. This disintegrant is widely used in tablets, capsules, liquids and pellets.

Other common uses for this compound include additives in nutritional supplements such as products aimed at building muscle mass and fat burning. It is odorless, tasteless and white in color. Medication containing this compound should be kept in a container with a lid. This product can absorb moisture in the air and thus could affect the potency of the active ingredients.


Sodium CMC is used in delayed release medication. The amount of this product in medication determines the rate of drug absorption. The medications absorption rate is calculated to ensure full tablet disintegration at the proper point in the digestive tract for optimal medical benefits. This common filler starts breaking down in the GI tract typically within 10 minutes and continues to disintegrate allowing the active ingredient to mix with the gastrointestinal fluids. As the active ingredient absorbs, the Sodium CMC fully dissolves in the digestive tract.


Medications containing Sodium CMC typically have a smooth texture ensuring ease of swallowing. This texture also allows for the stability of the medication to reduce breaking or crumbling before ingesting. The thickness of the tablet could indicate how much of the compound is included in the medication, but since it is often included in capsules and liquids the proper amount for each active ingredient will differ.


Sodium CMC can be manufactured from cotton, corn, or wood pulp. This product is considered one of the more gentle disintegrates on your digestive system. It is considered safe for individuals to ingest. Allergic reactions to this disintegrant are rare. Patients with Gastrointestinal problems usually show no ill effects from this compound, but it could cause undesired effects for individuals with Celiac disease.


If you suffer from Celiac disease, you should contact the manufacturer to determine whether the Sodium CMC was manufactured from corn. If it was derived from cotton or wood pulp, it should not contain sugar or starch and will be safe for medical use. Symptoms that might indicate the compound contains gluten are diarrhea, bloating, and severe stomach pain. Speak to your prescribing doctor about possible concerns.


Croscarmellose Sodium is widely used in the United States and has been approved for numerous medical formulas on the market today. While few people suffer from issues with this compound, it is important to discuss any questions you might have with your health care professional before starting a medical regime. Sodium CMC used in the USA does not contain GMO and should be considered safe in most medications and over the counter supplements.

note: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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