What is Sodium Starch Glycolate?
Sodium Starch Glycolate (also known as SSG) is a salt originating from such foods as corn, wheat, and rice, but is most commonly synthesized from potatoes. It is classified as a pharmacologically inactive substance. This salt is white in color and both tasteless and odorless, making it a common ingredient in pharmaceutical drugs.
SSG is a popular dissolution excipient. Dissolution excipients are responsible for aiding in the rapid digestion of pharmaceutical tablets and capsules. When a drug containing SSG is swallowed, SSG quickly absorbs water in the stomach to help the capsule or tablet dissolve. This means SSG is responsible for the effectiveness of the active ingredient in a drug; with the wrong amount of SSG, the active ingredient might not work as intended. Studies show that tablet compression pressure, the most common type of pharmaeceutical compression used in North America, has little effect on a capsule's disintegration time.
The lack of flavor present in SSG helps disguise any unpleasant taste or odor associated with active ingredients. This is beneficial in particular for consumers who are sensitive to the aftertaste of certain medications. While it's important to store medications in airtight containers like pharmacy bottles or individual day-of-the-week boxes, SSG's binding properties keep pills from being damaged by moisture in the air if they are left out in the open for short periods of time. SSG can be utilized whether the processing plant uses direct compression or wet granulation.
Along with being a dissolution excipient, SSG also aids in the stability of individual tablets and capsules. It bonds to active ingredients in order to keep them flowing and unbinding to other flowing molecules within the drug. Moreover, SSG is responsible for the ability to store multiple pills and capsules within a container without them sticking to each other or melting.
Sodium Starch Glycolate is a popular dissolution excipient thanks to the fact that its physical properties have a shelf life of up to three years, thereby extending the life of a medication and saving money for both producers and consumers. Proper handling techniques of medications containing SSG include storing the tablets or capsules inside airtight containers and ensuring proper room temperature at all times.
All inactive ingredients in a drug are specially formulated with safety of the consumer in mind. SSG is a safe and stable inactive substance used to help active ingredients work the way they are intended by pharmacists and developers.
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note: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.